MS spasticity is a common symptom that causes muscle stiffness, tightness, and involuntary spasms, which can range from mild twitching to painful cramping that interferes with daily activities and sleep. It happens when MS-related nerve damage disrupts signals between the brain and muscles, leading to overactive muscle contractions, most often in the legs and lower body. Spasticity can be triggered or worsened by heat, fatigue, infections, stress, tight clothing, or lack of movement, and symptoms may fluctuate throughout the day or worsen at night. Management typically includes medications, physical and occupational therapy, assistive devices, and self-care strategies aimed at reducing stiffness, improving mobility, and lowering fall risk.

