Switching MS treatments is common, and it usually happens when a current therapy isn’t controlling symptoms well, causes difficult side effects, becomes hard to manage, or no longer fits someone’s life circumstances. Because MS and its treatment options vary widely, any change should be made with your care team, who will consider disease activity, safety, and personal goals. Reasons to switch may include new relapses, MRI changes, infection risks, lab abnormalities, trouble sticking to the medication schedule, financial barriers, or pregnancy plans. Since each therapy works differently and may require a washout period, doctors help guide the timing and safest way to transition.

